Diabetes: Phenotyping and etiologies

This program is dedicated to developing of a common phenotyping grid between pediatrics and adult diabetology, and to centralizing the phenotyping of circulating immune cells for an optimized use of data by clinical research units.

Subclassification of individuals with adult-onset diabetes. Individuals who would traditionally be classified as having T1D, LADA or T2D were subgrouped using a data-driven approach based on six commonly measured variables known to reflect central disease mechanisms. Individuals with known monogenic or secondary diabetes were excluded since they already have a well-defined diabetes type. The resulting subtypes could allow clinical support, with better prediction of risk of complications and response to therapy, and improved power and specificity in scientific endeavors by enabling studies in more homogeneous patient groups.

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© Society for Endocrinology 2021

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A new article from Cécile Haumaitre and collaborators discusses the origin of pancreatic lesions associated with pancreatic cancer

A new article from Cécile Haumaitre and collaborators discusses the origin of pancreatic lesions associated with pancreatic cancer

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Pancreatic ductal adenocarcinoma is currently the fourth leading cause of cancer death worldwide. It is projected to become the second leading cause of cancer death by 2030. Unfortunately, PDAC is often diagnosed at an advanced stage, resulting in a 5-year survival rate of less than 10%. Since the most common precancerous lesions of PDAC are currently not clinically detectable, understanding the mechanisms that lead to their formation and progression is crucial to enabling early diagnosis and more effective therapeutic intervention.

Journée Thématique SFD

Journée Thématique SFD

la Journée Thématique de la SFD aura lieu cette année le 15 décembre 2023 à l’Institut Pasteur de Paris, et sera consacrée au sujet «Diabète, îlots et Insulino-Sécrétion».