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Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

To explore whether peripheral organ circadian clocks may affect the central pacemaker, Anne-Sophie Delbes et al. used a chimeric model in which mouse hepatocytes were replaced by human hepatocytes. Liver humanization led to reprogrammed diurnal gene expression and advanced the phase of the liver circadian clock that extended to muscle and the entire rhythmic physiology

The 59th EASD Annual Meeting

The 59th EASD Annual Meeting

The 59th EASD Annual Meeting will take place as a hybrid congress.
Tuesday, 3 October – Friday, 6 October 2023
Hamburg Exhibition and Congress
Messeplatz 1, 20357 Hamburg, Germany

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