Nov 12, 2023 | Diabetes Institute, Functional pancreatic beta cell mass in rodent and human, Publications, Research, T-cell tolerance, biomarkers and therapies in type 1 diabetes
A collaborative work between the teams of R Mallone and R Scharfmann leaded by L Rachdi indicate that TRP could induce immune tolerance to β cells by promoting their immune evasion through HLA-I downregulation and PD-L1 upregulation.