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Functional pancreatic beta cell mass in rodent and human

Tryptophan metabolism promotes immune evasion in human pancreatic β cells

Tryptophan metabolism promotes immune evasion in human pancreatic β cells

Nov 12, 2023 | Diabetes Institute, Functional pancreatic beta cell mass in rodent and human, Publications, Research, T-cell tolerance, biomarkers and therapies in type 1 diabetes

A collaborative work between the teams of R Mallone and R Scharfmann leaded by L Rachdi indicate that TRP could induce immune tolerance to β cells by promoting their immune evasion through HLA-I downregulation and PD-L1 upregulation.  
From the Scharfmann ‘s Lab

From the Scharfmann ‘s Lab

Dec 20, 2022 | Diabetes Institute, Functional pancreatic beta cell mass in rodent and human, Publications

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