News
News
A new article from Cécile Haumaitre and collaborators discusses the origin of pancreatic lesions associated with pancreatic cancer
Pancreatic ductal adenocarcinoma is currently the fourth leading cause of cancer death worldwide. It is projected to become the second leading cause of cancer death by 2030. Unfortunately, PDAC is often diagnosed at an advanced stage, resulting in a 5-year survival rate of less than 10%. Since the most common precancerous lesions of PDAC are currently not clinically detectable, understanding the mechanisms that lead to their formation and progression is crucial to enabling early diagnosis and more effective therapeutic intervention.
Congrès de la SFD 2024
Tarifs préférentiels jusqu’au 31 janvier 2024. Retrouvez toutes les informations du congrès
Journée Thématique SFD
la Journée Thématique de la SFD aura lieu cette année le 15 décembre 2023 à l’Institut Pasteur de Paris, et sera consacrée au sujet «Diabète, îlots et Insulino-Sécrétion».
Journée Scientifique conjointe Institut du Diabète et Graduate School METOD
Keynotes of Stefan Trapp (University College London) and Marc Donath (University of Basel)
Discovery of new rare genetic forms of obesity
This study, from Ralf Jockers and Julie Dam’s team as part of a European network for the prevention of childhood obesity, OBELISK,defines impaired GLP1R cell surface expression as a risk factor for traits associated with type 2 diabetes and obesity and provides potential treatment options for GLP1R LoF variant carriers.
Tryptophan metabolism promotes immune evasion in human pancreatic β cells
A collaborative work between the teams of R Mallone and R Scharfmann leaded by L Rachdi indicate that TRP could induce immune tolerance to β cells by promoting their immune evasion through HLA-I downregulation and PD-L1 upregulation.
Serotonergic neurons are involved in the counter-regulatoryresponse to hypoglycemia
Christophe Magnan and Céline Cruciani-Guglielmacci in collaboration with the team of Xavier Fioramonti highlight a new neuronal network involved in the regulation of the counter-regulatory response In particular, this study shows that DR 5-HT neurons detect iatrogenic hypoglycemia in response to the increased insulin level and may play an important role in this regulation.
EASD 2024
Detailled information on the registration process and access to the registration system will be available in early 2024.
Events
